Sunday, March 22, 2020

It Seems To Me We Need To Dramatically Ramp Up Our Approach To COVID-19 If We Are To Avoid Disaster.

Few will know that my very first degree, many, many years ago was in Immunology and Bacteriology and so, as you can imagine, I have watched the COVID-19 saga very closely.
As international experience has been accumulated it has become clearer and clearer that going hard and fast with isolation and distancing will help save lives and avoid illness.
It is also clear that no-one is immune from this virus, so we all need to be careful.
The other point that is worth making is that earlier today the Prime Minister has made it clear that much more draconian restrictions and isolation requirements are coming!
Others have offered similar views and I think action is needed sooner rather than later.
From the Conversation we have:

The case for Endgame C: stop almost everything, restart when coronavirus is gone

1.       John Daley
Chief Executive Officer, Grattan Institute



Nobody likes talking about the COVID-19 endgame, but we need to choose one. The appropriate interventions - public health, government spending, and freedom of movement - all depend on the endgame we choose.
The differences between endgames amount to tens of thousands of avoidable deaths, hundreds of thousands of avoidable hospital admissions, and deep and systemic impacts on Australia’s economy and society.
Many discussions are underestimating the likely political reactions when death counts rise.
They are also underestimating the economic and social consequences of an open-ended epidemic that will have enormous real-world impacts on small and medium businesses, as well as many not-for-profit organisations in every sector of the economy and society. We are not facing up to the social consequences if many close, and credit markets collapse.
We see three possible endgames.
None is attractive, but one is better than the others.

Endgame A: ‘flatten the curve’

Endgame A is the plan to “flatten the curve” – restricting movements in order to lower the peak in cases, while accepting that infections will continue to grow until the epidemic has run its course. There will be many deaths.
Imperial College has demonstrated that even if Britain flattens the curve, the peak months would still overwhelm hospital intensive care capacity, (particularly ventilators) by eight times instead of 30, perhaps halving the ultimate death toll.
Australia is also likely to run out of intensive care capacity when there are about 45,000 infections - a small fraction of the population.
In reality, political economy will probably get in the way of continued growth of infections. Public pressure to “shut everything” will become overwhelming as infections rise and hospitals struggle. But by then, with exponential growth in infections from a greater base, the containment challenge will be much greater.
Once infection rates fall in response to the shutdown, there is a risk of public pressure to open again too early, increasing infections until the death rate again becomes unacceptable – what economist Tyler Cowen has dubbed the “epidemic yoyo”.
Whether that happens or not, flattening the curve will require us to suppress economic and social activity for at least 12 months, and possibly much longer. The economic - and social - cost will be enormous.
No matter how much money governments throw at the economy, most businesses cannot survive the absence of normal activity for more than a few months.
It is not just tourism and hospitality. Companies small and large across sectors from household services to manufacturing to construction, are developing and executing plans to sack hundreds of thousands of people.
Unemployment will soar, probably driving a sharp fall in house prices, causing big problems for banks.
A variant of Endgame A is to isolate everyone over 60 (the age group most at risk), infect as many younger people as possible, and then hope that the disease dies out.
It’s not really plausible. There would be continued pockets of infection in many places, and they would quickly turn into localised outbreaks, particularly in nursing homes. It would be very hard to keep everyone over 60 separate from the people who provide them with food and services (who are likely to get infected) for months.
And of course there will be some deaths among those under 60.

Endgame B: ‘trace and track’

Endgame B is to trace and track every infection, something governments are trying to do.
But as NSW has now discovered, with thousands of potentially infected people getting off planes every day, and little enforcement of voluntary isolation, it’s easy for untracked infection to take off, and then it becomes practically impossible for subsequent tracking to shut it down. It is too easy for the number of new infections to overwhelm the tracking system, and then we are back in Endgame A.
Endgame B is only plausible if you start with very few infections and have sealed borders. Tasmania is now in that world, but other Australian states are not.

Endgame C: ‘stop then restart’

Endgame C is to “stop then restart”. This means minimising activity and interactions, and sealing the borders to passenger traffic including citizens (although not trade), until infections are driven down to zero.
Only essential services would be maintained (particularly the food supply chain and utilities such as electricity, water and the internet).
There is no point trying to finesse which strategies work best; instead the imperative would be to implement as many as possible at once, including closing schools, universities, colleges, public transport and non-essential retail, and confining people to their homes as much as possible.
Police should visibly enforce the lockdown, and all confirmed cases should be housed in government-controlled facilities. This might seem unimaginable, but it is exactly what has already happened in China, South Korea and Italy.
Once infections are at zero, and stay there for a fortnight or so to ensure there are no asymptomatic cases, economic and social activity can restart sequentially, although international borders would have to remain closed to passenger traffic until there is a vaccine.

We’re better at tracking people

Governments would also need to implement widespread testing and tracking to identify and squash any recurrence (something the shutdown would give them time to set up and improve).
This will be much easier once we are not dealing with a continued flow of new infections from passenger traffic.
Some epidemiologists, such as those from Imperial College, dismiss this approach, saying renewed large outbreaks are “inevitable”. But that is only based on history and past measures to track and trace. Today’s have no precedent.
We don’t yet have China’s ability to track and trace. But in a national emergency, setting up systems to track people and their contacts using mobile data might be worth both the money and the invasion of privacy.
While some people would like to execute this strategy without shutting passenger borders hard and for a long time, it is not plausible.
Even today, almost half of Australia’s new cases are getting off planes, and every one of them increases the risks of recurrence. Mere voluntary isolation is nothing like safe enough.
An alternative might be to allow Australian citizens to enter, provided they go into enforced isolation in a quarantine station room – for which airport hotels could be repurposed.

China, South Korea and Tasmania are doing it

In effect, Endgame C appears to be the strategy of China and South Korea – and domestically Tasmania is heading in the same direction.
Endgame C appears to be working so far in China, where the only new cases on Thursday were incoming passengers, each of whom is required to spend 14 days in supervised isolation in a designated hotel.
In Endgame C, it is plausible the shutdown would only need to last about eight weeks.
The mathematics of exponential growth also work in reverse: if the infection rate is below 1, instead of above 2 as it is now, then large numbers of cases turn into small numbers quickly.
China went from 4,000 new cases per day to 20 per day in six weeks with an infection rate that dropped below 0.5.
In Australia, if we achieved an infection rate of even 0.8, new infections per day would reduce from 100 to 10 in about six weeks, at which point track and trace becomes much more effective.
If Endgame C is the dominant strategy, it makes sense to implement it immediately and aggressively. The longer we wait, the longer that economic activity has to remain at a standstill to get back to zero cases.

Endgame C could offer hope

Endgame C isn’t pretty. Until a vaccine is deployed - and we’re punting that there will be a vaccine - there will be no meaningful international travel, tourism or students for at least 12 months. But most of these those things won’t be happening under Endgames A or B either.
At least Endgame C would allow domestic travel and tourism, hospitality, and other domestic activity once the shutdown was over. If our major trading partner – China – also successfully executes the same strategy, our major exports might continue as well.
More importantly, if it is communicated clearly, Endgame C would give businesses a plausible end date.
They would have a reason to hang on if government intervenes to tide them over.
Measures might include forgiving taxes, paying a fraction of wages (but also requiring employees to be paid less overall), mandating big temporary rent reductions (landlords are typically better placed to absorb losses than small businesses), providing loans, and encouraging – or requiring – banks to suspend loan repayments and perhaps interest payments.
Psychologically, it would provide genuine hope. We should aim for eight weeks, and provision for twelve in case it is harder than we expect.

An eight to twelve week shutdown

That relatively short duration would enable governments to intervene better to hold society and the economy together.
The government’s strategy would focus on providing a large social insurance policy that tides people and businesses over until the shutdown ends.
The goal would be to ensure we emerged out of the trough with human and physical capital and institutions in good shape. We need to avoid deskilling and demoralising workers and destroying businesses that will not be reborn easily.
This will require very large expenditure from government, which the government can afford if the shutdown is short enough.
Endgame C is not available to every country. The disease has already spread too far in Iran, and may have done so in the United States. It’s a difficult strategy for countries with big land borders with neighbours that let the disease run.

Australia can do it, though others cannot

Australia has the advantage of being an island, with a major trading partner that seems to be adopting the same strategy. This time around, we might be the less unlucky country – if we can act quickly and decisively.
It’s possible that Endgame C might not work. Despite our best efforts, we might not be able to reduce infections, or the disease might recur when we think it has been eliminated.
But the costs of giving it a try are relatively low – in both lives and economic costs – compared with Endgame A.
In the worst case, it gives us more time to increase critical care capacity and prepare for Endgame A.
The logic is compelling: if we’re not going to pursue Endgame C (stop then restart), at the very least authorities ought to explain why it is not technically possible.
Each of the endgames are unpleasant. COVID-19 is the real-life “trolley problem” in which someone is asked to choose between killing a few or killing many.
When any of us are presented with the trolley problem, the all-but universal response is to refuse to choose.
That is what we are doing at the moment, and it will just make our problems worse.
We should recognise this psychology, and decide to choose the least-bad endgame.
The faster we do it, the less bad it will be.
Here is the link:
Also we have this:

Coronavirus: Even glass-half-full optimists can do the maths

 “Do the maths.” Whether intentionally or otherwise, in just three words, Deputy Chief Medical ­Officer Paul Kelly highlighted the gravity of the coronavirus in a way no politician has been willing to.
It’s the projected death toll that is most staggering. Indeed, that ­reality, and how profoundly it will impact on the Australian and global societies, is at the heart of the panic that has engulfed the planet.
Make no mistake: we are living through extraordinary times. And as one government MP said to me during the week: “We aren’t even at the end of the beginning yet.”
Doing the maths as to how many among us might fall victim to this virus is truly mind-boggling. We are constantly being told to ­listen to the experts. Hear what the medical professionals have to say. It is those same experts who say that the virus could easily infect between five million and 15 million Australians. Their assessment is that the genie is most likely already out of the bottle, and hopes of containing the virus such that it doesn’t spread so dramatically are wishful thinking.
Do the maths.
Politicians are hopeful that Australia’s infection rate can be slowed down — which is the so-called flattening of the curve. It’s not about containment. Rather, the aim is merely to spread out the time period during which so many of us catch the illness so that the hospital system can cope. That matters because exactly how well or badly the hospitals handle the crisis has a direct impact on the mortality rate.
If we do well, the mortality rate might match South Korea’s 0.7 per cent rate. In other words 7000 people die for every million who contract the virus.
While the government might want to stay glass-half-full and point to the fact that 80 per cent of people who are infected have only mild symptoms, that leaves one in five people who get it doing worse than that.
If between five million and 15 million Australians are infected, doing the best-case maths on the mortality rate to follow would mean 35,000-105,000 Australians will die from the coronavirus.
I have heard shock jocks play down the risks, pointing to how many Australians get cancer in their lifetimes and so on. But these figures are based on infections over the next six months, not over many decades.
What all nations are hoping to avoid is matching what has happened to Italy, where the virus is not only spreading rapidly but the mortality rate is closer to 7 per cent.
Do the maths.
Much more here:
Next some really current graphs that are self-explanatory.
  

To me, as a biological scientist and physician the evidence is pretty conclusive and we really need to move to much tighter restrictions ASAP, or we will all be in pretty big trouble.
(Sorry, in advance, this is not Digital Health. This is rather a bigger issue in my mind!)
David.

10 comments:

  1. There might be two costly lessons come out of this

    1. We seem to lack the ability to govern or be governed. The complete lack of respect in what our governing institutions are saying exposes a rapid breakdown in the relationship between the people and its representative houses. Long have we lived with spin and BS, it is almost like the little villager that cried wolf.
    2. Our actual real and meaningful health system has like many countries been for too long, underfunded, poorly equipped and diluted of funds ( too much gone into far too expensive ‘systems of record” tech). We can no longer run health on Agile and Lean thinking. The current events show that our current health system lacks capacity and capability. It's a bit like the cheap private health insurance you buy to avoid tax penalties but do not cover the people on the policy for much.

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  2. Anon March 22, 4:57 PM. You might find this article interesting.

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  3. @8:46 P What article are you referring to?

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  4. Yes the link might help thanks

    https://www.project-syndicate.org/commentary/greater-risk-literacy-can-reduce-coronavirus-fear-by-gerd-gigerenzer-2020-03

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  5. As a counter to the current doom and gloom being peddled on the rating chasing 24/7 news and media. Looking at the recovery rates are good. Preventative measures might be helping along with those magnificent people in healthcare. Hopefully, all governments start wisely investing and remove some who pillage health budgets with over proceed underperforming products and services

    1,300 - Currently Infected Patients
    1,298 (100%) - in Mild Condition

    2 (0%) - Serious or Critical

    Source: https://www.worldometers.info/coronavirus/country/australia/

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  6. Anon @ 8.37am

    Don't forget the 7 deaths so far....on the same page.

    David.

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  7. Long Live T.38. Thank you for the link to the article. It is a well written set of points-of-view.

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  8. The $2 billion spent on My Health Record could buy a lot of ventilators.

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  9. That article is astonishing. Still with the 'flu is worse' PoV, while advising people should have good risk literacy... wow.

    As with a lot of other things: this won't age well

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  10. I think the author is not saying "flu" is worse, but pointing out that we do not react to other serious events as we seem to be with this "pandemic" for the average person on the street it is puzzling. In that context the author highlights a trait in human nature.

    I guess now it is hitting less developed parts of the world that are not as well placed to "shut-down" how well herd immunity might work.

    I am not advocating for any one position I am sure there will be time enough for reflection in the not to distant future.

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